Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications. Kalsner L1,2, Twachtman-Bassett J1, Tokarski K2, Stanley C3, Dumont-Mathieu T1,2, Cotney J2, Chamberlain S2. Abstract BACKGROUND: Genetic testing of children with autism spectrum disorder (ASD) is now standard in the clinical setting, with American College [...]
Yang F1,2, Chen J1, Miao MH1, Yuan W1, Li L1, Liang H1, Ehrenstein V2, Li J2. Abstract OBJECTIVE: The present study aimed to examine the association between paternal selective serotonin reuptake inhibitor (SSRI) use before conception and the risk of autism spectrum disorder (ASD) in offspring. DESIGN: A population-based cohort study. METHODS: We conducted a [...]
Examining the Links Between Challenging Behaviors in Youth with ASD and Parental Stress, Mental Health, and Involvement: Applying an Adaptation of the Family Stress Model to Families of Youth with ASD. Schiltz HK1, McVey AJ2, Magnus B2, Dolan BK2,3, Willar KS2, Pleiss S2,4, Karst J2,5, Carson AM2,6, Caiozzo C2, Vogt E2, Van Hecke AV2. Abstract [...]
Yang Y1, Tian J2, Yang B3. Abstract Autism spectrum disorder (ASD) is a severely neurodevelopmental disorder that impairs a child's ability to communicate and interact with others. Children with neurodevelopmental disorder, including ASD, are regularly affected by gastrointestinal problems and dysbiosis of gut microbiota. On the other hand, humans live in a co-evolutionary association with [...]
McDermott JH1, Study DDD2, Clayton-Smith J3, Briggs TA4. Abstract A diverse range of genetic aberrations can lead to Autistic Spectrum Disorder (ASD) and many of these have been identified via Next Generation Sequencing (NGS) as part of large scale consortium studies. ASD is a phenotypically variable disorder and detailed clinical descriptions are essential to appreciate [...]